ABSTRACT
The COVID-19 pandemic has led to significant changes in the provision of medical care, clinical management of pregnant women and newborns. Starting from the first, general "temporary” methodological recommendations, followed by specialized ones for pregnant women and newborns and children older than a month, interpreted the clinic, diagnostics, tactics due to the knowledge that was at the moment, but the availability of medical resources changed, new scientific data appeared and approaches to understanding the problem continued to develop. Objective – to evaluate maternal, perinatal and neonatal outcomes in the incidence of COVID-19 in the Khabarovsk Territory in the period from 2020 to 2021 [before the mass spread of Omicron strain SARS-CoV-2 (SARS-CoV-2 Omicron)]. Material and methods. A retrospective analysis of operational information for the entire period of COVID-19 morbidity in the Khabarovsk territory from March 11, 2020 to December 25, 2021 was carried out according to established reporting forms, including demographic indicators of the region and statistical data on COVID-19 for pregnant women, women in labor, women in labor, and children. Results. For today, the most prominent negative outcomes of COVID 19 during pregnancy and puerperal period are premature birth and stillbirth. Medical premature termination of pregnancy is usually indicated in severely affected hypoxic mothers. Unfavorable neonatal outcomes from infected mothers are mainly caused by complications of prematurity and concomitant diseases. Taking into account the hypoxic and infectious origin of placental pathology, detected in placentas of COVID-19 – infected mothers, a possibility of long-term complications should be considered. Conclusion. The perinatal period in COVID-19 is the period with the most unfavorable pregnancy outcomes for a mother-fetus couple, while newborns and young children are not at high risk of developing a severe course of COVID-19 infection. © 2022 by the Author(s).